Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
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چکیده
منابع مشابه
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
BACKGROUND Juglone is a natural pigment, which has cytotoxic effect against various human tumor cells. However, its cytotoxicity to glioma cells, especially to tumor stem-like cells (TSCs) has not been demonstrated. METHODS TSCs of glioma were enriched from U87 and two primary cells (SHG62, and SHG66) using serum-free medium supplemented with growth factors, including bFGF, EGF and B27. After...
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ژورنال
عنوان ژورنال: BMC Neurology
سال: 2017
ISSN: 1471-2377
DOI: 10.1186/s12883-017-0843-0